How successful is IVF?

The success rate of IVF treatment is often expressed as the percentage of women who get pregnant as a result of the procedure. Specifically, the proportion of successful IVF births compared to the total number of embryo transfers (ET) is calculated in this fashion.  Live births achieved via IVF are a success.It has been reported by the All India Institute of Medical Sciences (AIIMS) that the success rate of IVF in India is between 30 and 35 percent. Based on the number of IVF cycles completed in their clinics, the different multi specialty and single-specialty clinics have success rates to report. The success rate of IVF varies from clinic to clinic, and these variances are due to the many variables that influence the outcome of the procedure.

Factors that may have an impact on the success rate of IVF

Even while it is necessary to have a thorough awareness of the possible IVF success deciding variables, it is also crucial to note that IVF results and methods vary across couples and facilities. It also relies on the number of IVF efforts conducted as well as the number of adjustments made between each attempt.

Age

The age of the spouse is the most important factor in determining the effectiveness of IVF. The quality of eggs produced by older women (those above the age of 35) declines dramatically as they become older. According to statistics, the likelihood of a successful IVF procedure in young women is over 40% worldwide (below the age of 35). Women between the ages of 38 and 40 had a 23 percent chance of becoming pregnant with IVF, compared to just 10% of women beyond the age of 40.

When it comes to the age issue in males, men over the age of 40 may see a decrease in sperm count and quality, which may negatively affect their chances of having a successful IVF cycle.

The type and duration of fertility

The factors that contribute to infertility have a critical role in determining the success rate of IVF. These reproductive parameters determine the quality and quantity of gametes, which are then responsible for the quality of embryos and the effectiveness of IVF procedures in the future. Certain infertility issues are hereditary, congenital, or acquired via infections, and these issues must be addressed first before undergoing IVF therapy to ensure a successful outcome.

However, some factors, including the existence of twin ovaries, uterine abnormalities, fibroids, cysts, and ovulation difficulties, may make it more difficult to achieve a favorable pregnancy outcome. Furthermore, if the infertility problem has been present for a long period of time, this may result in difficulties that impair the odds of having a successful IVF cycle.

Other complications

Conditions such as high blood pressure, diabetes, vitamin D deficiency, and other health problems are more likely to have an impact on IVF results. The endometrium of the uterus is also a significant factor to consider. It is necessary for the endometrium to maintain a thickness of at least 7 mm in order to increase the likelihood of successful IVF implantation.

The quality of eggs, sperm, and embryos

It is considered that using high-quality eggs may aid in the production of high-quality embryos. Furthermore, the quality of the egg determines the quality of the embryo to a remarkable degree (almost 95 percent). As a result, a woman must produce eggs of superior quality. While there are many variables that influence egg quality, age, fertility, and ovulation state are the most significant. Men’s sperm counts, morphology, and motility are all important factors in determining the quality of embryos, the rate of fertilization, and the likelihood of a successful IVF cycle.

The total number of IVF attempts

The success rate of IVF rises as the number of IVF trials increases. It is possible to have a successful IVF cycle on the very first try of the procedure. However, if you are planning a second IVF round, your odds of becoming pregnant and having a successful IVF cycle will certainly improve. According to studies, a total of three IVF rounds raises the likelihood of achieving a pregnancy with IVF by 45-53 percent. As a result, the National Institute of Health and Care Excellence (NICE) advises three IVF cycles for women under the age of 40 as a clinically and financially reasonable quantity.

Considerations for Donors

IVF provides a fantastic opportunity to examine donor inclusions. Depending on the reproductive state of the couple, the use of donor eggs, sperm, embryos, or a surrogate may significantly boost the odds of a successful IVF procedure.

The IVF center 

The facilities and amenities given by the IVF Center might also have an impact on the success percentage of the IVF procedure.The integration of complex ART procedures into routine treatments, together with well-established and cutting-edge IVF methods, is a step forward. The expertise and experience of the IVF specialist in dealing with difficult fertility challenges are essential. IVF is a method that requires a great deal of laboratory work. The presence of an in-house laboratory, cryopreservation units, and a comprehensive range of infertility treatments at an IVF clinic may aid in the delivery of superior IVF results.

IVF and sophisticated ART techniques

The majority of the steps of IVF are carried out in vitro or under sterile settings. Every step of the IVF process needs thorough monitoring and exact administration. Whether it’s the continual observations made throughout,
  • Ovarian stimulation, among other hormonal therapies,
  • Gamete and embryo selection that is viable,
  • Embryos are transferred with extreme caution.
  • Alternatively, the uterine receptivity/conditions at the time of transfer

All of these criteria are critical in determining IVF success rates. ART techniques that are more advanced, such as ICSI, IMSI, and Blastocyst culture, remove fertility factors. When it comes to preimplantation genetic diagnosis/screening (PGD and PS), the preference is for genetic screening of embryos. Assisted laser hatching is a technique that assists in the artificial hatching of embryos. These improved methods allow for successful gamete selection and lead to an increase in the success rate of IVF treatments.

A person’s way of life and his or her habits

Diet, exercise, and good living habits all play a role in maintaining healthy reproductive systems throughout IVF. The evidence suggests that oxidative stress, which is created by unhealthy lifestyle variables such as tobacco use, excessive alcohol consumption, and poor eating habits, might have an influence on IVF success and live birth rates.

Takeaway

Understanding the IVF success rate and the elements that influence it might be helpful when deciding whether or not to proceed with the procedure. However, it is important to remember that every IVF procedure is different, and the chances of a successful IVF procedure vary from person to person. If you are considering IVF treatment, you should first determine your odds of success via a professional examination before deciding on an IVF protocol and advanced IVF technology considerations.



Location: J. P. Nagar, Bengaluru, Karnataka 560078, India

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